Replacement for Lifespan Extension

Replacement is an engineering approach to aging that requires fewer fundamental advances in discovery in aging/biology.

Whole body replacement via cloned or synthetic embryo with neocortex knockout for head or brain transplant.
Progressive brain replacement via stemcell-based tissue engineering.
Total replacement of aged body parts with lab-grown young parts.

LBF Replacement Roadmap

HydraDAO Objectives

Progressive Brain Replacement

Replacement of aging brain tissue, minimizing disruption to cognitive function and allowing gradual replacement without loss of identity or memory.

Body Transplant Process

Refine and surgical techniques for head/brain transplants.
Automation for scaling and precision.

Limb Regeneration

Activation of stem cells and tissue scaffolding to initiate and guide regrowth of complex tissues.
Use of growth factors, gene editing and bioelectricity to replicate regenerative capabilities similar to those found in species like axolotls.

Cloned Non-Sentient Bodies

Develop and test gene editing for clone neocortex knockout.
Achieve near zero false-negative knockout rate.

Bioprinting

Scaled production of bioprinted organs using organ-specific bioinks.
Ensuring vascularization and functional integration within printed organs.

Xenotransplantation

Genetic modification of donor animals to prevent rejection and enhance compatibility.
Development of protocols to induce immune tolerance in human recipients.

...and much more.